Chad Concelmo had posted a lengthy preview of Amanita Design's upcoming 2D adventure game Machinarium, right after spending some time with an early playable build at the IndieCade section of the E for All Expo in Los Angeles, California.

IndieCade will be held at Open Satellite next (in Bellevue, Washington) from October 10th to 17th.

Interesting tidbit from the article:

"..the game runs on a screen-to-screen basis, so every item you collect is found and used within the same screen – there is no need to carry anything with you or backtrack at all."

Machinarium: The best game you (most likely) have never heard of (Destructoid)
E for All 2008: Indiecade: Stupid Name, Cool Games (GotGame)